R. B. D. ; and U. S. Army Grant DAMD 17-94-J-41 15 to Z-H. L. ; . 2 To whom requests for reprints should be addressed, at NCI-Navy Medical Oncology Branch, National Naval Medical Center, 8901 Wisconsin Avenue. Building.
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Prolonged estrogen exposure may have a significant role in the development of breast cancer in older women. Bone contains estrogen receptors and is sensitive to manipulation of its density by serum levels of estrogen. Previous research has therefore suggested that bone mineral density BMD ; may serve as a powerful marker of breast cancer risk in elderly women, as it reflects the amount of long-term exposure to endogenous estrogen. Zmuda and colleagues hypothesized that this association may be true not only for early-stage breast cancer tumours, but advanced-stage as well. 8905 participants were assessed initially for BMD by single-photon absorptiometry at three locations: the proximal radius, distal radius, and calcaneus. The patients were then divided into quartiles based on their BMD values. The women were followed for a period of up to years 1986-1998 ; to determine subsequent development of breast cancer. Breast tumour incidence was found to increase with escalating BMD for each anatomical location. This was also true when BMD at the three locations was grouped together; women who were in the highest quartile for BMD at all three sites had a 2.8 times greater risk of breast cancer than women in the lowest quartile at all three sites. These findings persisted after adjustment for known and suspected breast cancer risk factors, such as age, body mass index, age at menarche and menopause, nulliparity and estrogen use. The strength of the association between BMD and breast cancer risk was also greater among women diagnosed with advanced breast cancer as compared to early-stage cancer. This suggests that biological factors associated with a high BMD may accelerate the growth rate and progression of tumours. On the basis of these results, the authors speculate that BMD, along with other risk factors, may serve as a useful marker in identifying women at high risk for breast cancer. This study also proposes an inverse relationship between osteoporosis and breast cancer, two of the most common conditions affecting the health of older women. Zmuda JM, Cauley, JA, Ljung B-M et al. 2001 ; . J Natl Cancer Inst. 93 12 ; : 930-936 and
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Sir, The warning about the danger of uncontrolled oxygen therapy during ambulance transfer needs to be extended to other frontline healthcare professionals including nursing staff ; , particularly in Accident and Emergency Departments and in Medical Assessment Units because they might not necessarily know any better in terms of awareness that, in acute exacerbations of chronic obstructive pulmonary disease COPD ; , unlike in other acute respiratory emergencies, it is not an appropriate response to turn up the oxygen supply to achieve a `normal' oxygen saturation SaO2 ; as opposed to the more appropriate SaO2 of 902% ; 2, 3 following a subnormal reading on pulse oximetry. Furthermore, in view of the coexistence of coronary heart disease CHD ; which accounts for 11267% of deaths in COPD cases ; , 4 frontline staff should specifically ask COPD patients and
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Eat regular meals based on starchy foods such as bread, pasta, potatoes, chapatti, rice and cereals. Enjoy plenty of fruits and vegetables every day.
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Or click the first letter of a drug name: a b c advanced search drugs & medications diseases & conditions pharmaceutical news & articles pill identifier drug interactions checker medical encyclopedia medical dictionary community forums welcome guest register or sign in my viewing history my drug list my interactions lists member offers consumer drug information medfacts terbutaline terbutaline generic name: terbutaline tablets ter-byoo-tuh-leen ; brand name: brethine terbutaline is used for: treating or preventing symptoms caused by spasms or contractions of the muscles around the bronchioles air tubes ; associated with asthma, bronchitis, and emphysema and
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Reducing the potential for skin necrosis and patient's imposed work of breathing. The AirLife soft, "Comfort-Fit" prongs and masks utilize advanced features like flexible bellows and anatomically contoured shapes that help provide an effective seal, reduce skin necrosis and increase patient comfort. The AirLife intuitive "Comfort Wrap" fixation device has five sizes to fit all of your patient's needs. The fixation device gently wraps around the patient's head and secures with adjustable closures for a custom fit that allows for single clinician application. The custom fit helps secure the generator at the proper angle, which helps reduce pressure points and minimize air leaks that can cause nuisance alarms. The AirLife generator incorporates unique, patent-pending "Vortice" technology and "Low-Momentum Impinging Jets" that effectively reduce the imposed work of breathing WOB ; during both inspiratory and expiratory efforts. When the patient begins to exhale, the destabilized air created by the "Vortices" allows the gas flow to be quickly and smoothly redirected to the exhalation tube, reducing the patient's imposed WOB. Minimizing a patient's WOB is extremely important in promoting quick recovery and healthy development for an infant. In addition, it helps calm the patient while allowing the infant to conserve precious calories needed for growth. The "Low-Momentum Impinging Jets" can entrain flow to meet the patient's inspiratory demand and deliver the gas at a lower momentum, which helps to provide a constant level of CPAP and reduces harmful noise levels around the patient. The AirLife driver features the latest advancements in respiratory technology to assist clinicians in delivering, adjusting, and monitoring nCPAP therapy for their patients. The "Comfort-Flow" feature allows the clinician to simply set the desired nCPAP pressure and the driver automatically adjusts the gas flow to achieve the desired result. This not only saves the clinician time by not having to manually adjust the flow to compensate for leaks, but it also maintains a constant level of nCPAP, providing the optimal level of therapy for the patient. The "Smart Alarm System" helps maximize patient safety and clinician efficiency by differentiating between critical and noncritical alarms while a message bar indicates which parameter is in alarm state. As the clinician sets or changes the operating parameters, the alarm values automatically adjust to the new settings, helping to reduce nuisance alarms. Patient Care Every component in the AirLife Infant nCPAP System has been engineered for maximum performance, reliability, patient comfort, and clinician ease of use. Patient comfort is an important factor in the neonatal care environment because the less discomfort a patient experiences, the greater the opportunity for healthy growth and development during this critical time in the patient's recovery. The AirLifeTM Infant nCPAP System incorporates an innovative design and patentpending technology to help minimize skin necrosis, reduce the patient's imposed work of breathing, and maximize patient comfort. The AirLife Infant nCPAP System is designed to help caregivers not only initiate this vital therapy quickly and easily; but also allow for precise adjustment and easy monitoring to help reduce nuisance alarms, allowing clinicians more time for patient care. Respiratory Therapy Vol. 1 No. 4 June-July 2006 and benazepril.
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Laboratories collectively announced that the new coronavirus was the cause of SARS. This sequence of events was an extraordinary and unprecedented example of international scientific cooperation and the power of modern science used to solve a new and serious problem. The authors dedicated the paper to the memory of Carlo Urbani, the World Health Organization infectious disease physician who contracted SARS in Hanoi and died on 29 March 2003 and betahistine.
| Brethine used in laborCorrespondence: Dr. A. Gafter-Gvili, Dept. of Medicine E, Rabin Medical Center Beilinson Campus ; , Petah Tikva 49100, Israel. Phone: 972-3 ; 937-6500; Fax: 972-3 ; 937-6512 email: anatga2 clalit .il, for example, neurontin.
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This range include the very small population from Eniwetak island Rongerik atoll ; collected in 1955. This population had disappeared by 1956, and the other two samples are from Rongerik island. The other four high tests include all tests involving the Rongelap population collected in 1956. The three tests falling below 56.6 include the very low Bikini and Rongelap populations and their heterozygote in 1955. The random-mated pairs within populations can be compared to the crosses between members of different populations in 1956 and 1957. The average egg development for random matings is 81.8 per cent range 74.9-88.3 ; , while that of crosses between populations is 77.3 per cent range 58.2-86.1 ; . With the two crosses between Majuro and Ponape removed, this value is 79.9 per cent. These crosses were not very successful either year, falling into the low classes with A X M, M and B X A for 1955, which involved the irradiated populations of Bikini and Rongelap. The three- and four-way crosses Fig. 2 and 3 ; showed the gain from heterosis and from having heterozygous parents. The average egg development was 84.2 per cent range 72.4-91.7 ; , with all three tests below 80 per cent development occurring in 1957 and involving the MB heterozygotes. There is another example of the superiority of the heterozygote in the 1955 tests. The heterozygotes between Bikini and Rongelap, Majuro and Bikini, and Rongelap and Bikini when inbred gave a better egg development by about 10 per cent than the averages of their parent stocks inbred. This was not true for the tests for stocks and crosses in 1956 and 1957. In those two years the average for all heterozygotes was almost identical with the averages of their parent stocks-in each case the detrimental factors could become homozygous in the eggs from the brother X sister matings. In 1955 the stocks seemed to carry factors homozygous ; , which reduced the effective egg development of their offspring. Discussion.-The thermonuclear device of March 1, 1954, was exploded seventeen months before our collections were begun in 1955. To show a genetic effect of irradiation on populations under these circumstances, it is necessary to establish the population cycles on both irradiated and control populations. If irradiation injured any of the populations enough to measure, we must establish this as an effect in addition to the other population fluctuations from year to year. It is necessary to establish consistencies in the data because laboratory environmental variations may mask or exaggerate differences. Differences in population structure may influence the decay of variability and the rapidity of natural selection in reducing any excessive burden of genetic abnormalities that might be produced. The D. ananassae population on Ponape is large and in competition with a number of other species of Drosophila. It has given very similar tests the two years Fig. 1 ; . The Majuro population is also fairly large, although very much smaller than Ponape. The Bikini population has been small and sparse all three years. The Rongelap population was larger, especially the second year, but was reduced the third year. The exceptionally large and vigorous population on Rongelap the second year occurred on the abundant fruit at the site of the native village. Much of the pandanus and papaya had been cleared away in rebuilding the village for the natives, who returned in June 29, 1957.2 The amount of fallen fruit was much reduced on that island in August, 1957, partially by the action of the animals brought in by the Marshallese. The population of Drosophila on Eniwetak in 1955 was much smaller than on the other islands and had disappeared by 1956. The population on Rongerik.
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