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10. K. Raine. Determinants of Healthy Eating in Canada: An Overview and Synthesis. Canadian Journal of Public Health. Other Published Papers and Reports: 1. Clark, A., Raine, K., Raphael, D. The ACS ADA AHA Joint Statement on Preventing Cancer, Cardiovascular Disease, and Diabetes: Where are the Social Determinants?, Diabetes Care. 27: 3024, 2004. L. McIntyre, T. Glanville, & K. Raine. Hungry mothers of barely fed children. Nutrition and Food Security Network Newsletter, Dietitians of Canada p.3-4, Summer 2002. L Intyre, K.D. Raine & J. Dayle. Benefits and barriers associated with participation in food programs in three low-income Ontario communities Letter to the Editor ; , Canadian Journal of Dietetic Practice and Research, 63 2 ; : 52, 2002. K. Raine. Poverty, ethnicity and type 2 diabetes. Clinical Review ; International Diabetes Monitor, 14 4 ; : 1516, 2002. K.D.Raine. Who's Doing Applied Diabetes Research . and on What? Diabetes Quarterly, Diabetes Educator Section Newsletter p 7, Summer 2000. M. Paquette & K. Raine-Travers. The Ideal Feminine Body. Practice. Published by Dietitians of Canada ; Issue #10, p.4., Summer 2000. B. Bechtel & K. Raine Travers. The cost of healthy living. In, Tracking the Trends: Social Health in Edmonton. Edmonton Social Planning Council, June 2000. B. Hodson, L. Anderson, D. Anderson, K. Raine-Travers & C. Shore. Evaluation of the Healthy Okotoks Project. A report to Alberta Health & Wellness, Health Transition Fund. June, 2000. K. Raine-Travers. A Sociology of Food and Nutrition: The Social Appetite, Germov, J. & Williams, L. eds. ; Book Review ; . Journal of Nutrition Education, 32 1 ; : 66-67, 2000. Quote nicole-brittany]i was wondering if you thought ventolin with a spacer ; would be better than briconyl turbuhaler hi - i use ventolin and atrovent ; with a spacer- works very well for you like, but the bricanyl may help better than the ventolin or vice versa. Stefansson is a prominent icelandic scientist and a co-author of the new england journal of medicine study.

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Assay of superoxide release. Extracellular superoxide production by PMA activated cells seeded in 96-well microplates was determined from the SOD-inhibitable reduction of cyt c. The assay reaction mixture was prepared in HBSS with 2.2 mg ml glucose immediately prior to use and 100l thereof added directly to the cells without removal of the 50l maintenance medium. The reaction mixtures were set up from stock solutions with concentration ranges of cyt c 20 - 320 M ; , SOD 50 - 300 U ml ; and PMA 1 - 32 M ; The final evaluated standard concentrations are based on the results of the present study. They are 160 M for cyt c, 100 U ml for SOD and for PMA 16 M as the most effective concentration. Absorbance was measured in a plate reader at 550 nm Anthos HAT II ; as endpoint after 20 min exposure ; and as kinetic readings 10 - 40 min ; . All experimental groups were set up in quadruplicates. Background values from cells in situ without assay mixture were 5% of the sample readings. Blind values were obtained by measuring standard mixtures without cells. The A550 values were converted to nanomoles nmol ; of cyt c reduced 106 cells, using a net E550, Red-Ox of 2.1 x 104 M-1 cm-1 Johnston, 1984 ; . Superoxide.

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Hydrate restriction can be effective in improving the atherogenic lipid phenotype. Relationship between obesity and the IRS Tracey McLaughlin Stamford, CA ; discussed the relationship between obesity and the IRS and potential approaches to treatment, reviewing the prevalence of obesity and noting that almost 5% of the population has BMI 40 kg m2. She noted that even persons with BMI 2325 kg m2 who are of Asian ethnicity, or of non-Asian ethnicity with insulin resistance, also usually require weight loss for optimal improvement. Insulin resistance is linearly associated with the BMI, although with wide scatter at any given level, so that 2530% of the variance in insulin sensitivity is explained by BMI. Fewer than half of persons with BMI between 30 and 35 kg m2 have an SSPG in the highest tertile, with 11% of obese persons actually being in the lowest SSPG tertile, while 13% of persons with normal 25 kg m2 ; BMI are in the highest tertile of SSPG. She suggested that the clinical challenge is to focus on those persons with both obesity and low insulin sensitivity. Glycemic abnormality was not sensitive in studies performed at Stanford, as 2.5% of those in the highest insulin sensitivity tertile, 7% of those in the middle tertile, and 30% of those in the lowest insulin sensitivity tertile had IGT. Insulin sensitivity is, however, clinically important, as persons in the most insulinresistant tertile had a 14% 5-year CVD event frequency compared with 2% of the middle tertile and none of the most insulin-sensitive group 38 ; . In study of 50 obese persons, 29 insulin resistant with mean SSPG 232 mg dl and 21 insulin sensitive with mean SSPG 84 mg dl, with similar age and BMI, the 2-h glucose was 144 vs. 112, triglyceride 199 vs. 125, and HDL 42 vs. 54 mg dl, with a triglycerideto-HDL ratio 5.4 vs. 2.5, suggesting that insulin resistance contributes to CVD risk independent of obesity. In a study of weight loss with a 4-month hypocaloric diet and sibutramine in 13 insulin-resistant vs. 11 insulin-sensitive healthy obese women losing similar amounts of weight, the SSPG decreased 34% in the insulin-resistant group from 210 to 140 ; , whereas it did not change at 80 mg dl ; in the insulinsensitive group, with the women whose insulin sensitivity improved having lower.

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To treat arrhythmias and high blood pressure. Bicuspid valve commonly called the mitral valve ; : One of the four valves of the heart located between the left atrium and the left ventricle, permitting blood to flow in one direction from the left atrium into the left ventricle. Calcium channel blockers: A class of drugs that block the entry of calcium into the muscle cells of the heart and the arteries. The drugs are used to treat angina, high blood pressure, and abnormal heart rhythms. Cholesterol: A steroid that is carried in the body as lipoproteins HDL high-density lipoproteins and LDL lowdensity lipoproteins ; . Elevated levels of LDL increase the risk of coronary artery disease. High levels of HDL reduce the risk of heart disease. Coronary arteries: Arteries that supply the heart muscle with blood rich in oxygen. Coronary artery disease: Characterized by the build up of plaque in the arteries that feed the heart muscle. As the plaque builds up, the flow of blood to the heart is reduced. CPR cardiopulmonary resuscitation ; : An emergency procedure used when an individual's heart has stopped. Defibrillation: The use of an electric shock, administered on the chest wall or directly to the heart muscle to restart or normalize heart rhythms. Diuretics: Any substance food or drugs ; that promote the formation of urine by the kidney. Diuretic drugs are used to reduce fluids in the body and to treat high blood pressure. Embolism: The obstruction of a blood vessel by a foreign substance or a blood clot. Fibrillation: A form of arrhythmia where the heart beats so fast that it is not pumping the blood through the heart. Hemorrhage: Internal or external bleeding or the abnormal flow of blood. High-density lipoproteins HDL ; : A cholesterol. Can I order my prescriptions through the mail? UPMC Health Plan has a contract with a mail-order pharmacy fulfillment center to offer you savings and the convenience of having prescriptions for maintenance drugs sent directly to your home. Maintenance drugs are drugs that you take on a regular, long-term basis. They include medications that treat high blood pressure, asthma, diabetes, arthritis, high cholesterol, and other chronic conditions. With this convenient mail-order service: s You receive a 90-day supply of most drugs, plus refills, as prescribed by your doctor. s You pay a lower out-of-pocket cost for a 90-day supply than you would pay at a retail pharmacy. s You enjoy strict quality and safety controls for every prescription filled. Please refer to your UPMC Health Plan prescription drug schedule of benefits for your actual prescription copayments. For a first-time prescription or a new medication, UPMC Health Plan recommends that you try a 30-day supply of the drug from a retail pharmacy before requesting a 90-day supply through the mail-order program. This approach reduces wasted medication and bicalutamide and bricanyl, for example, pregnancy.

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Bathula R, Chaturvedi N, Hughes A, Coady E, Francis D Imperial College, London, United Kingdom BACKGROUND: South Asians worldwide have a 1.5 fold elevated risk of coronary heart disease CHD ; than Europeans, partly explained by higher diabetes prevalence in South Asians. Diabetes is associated with reduced heart rate variability HRV ; and decreased baroreflex sensitivity BRS ; , which are predictive of increased CHD. This study aimed to investigate and explain ethnic differences in HRV and BRS. METHODS & RESULTS: 84 South Asian and 83 European men age 3575yrs ; , half with established CHD, underwent metabolic profiling and HRV BRS measurement. Mean RR interval was greater in South Asians than Europeans 1014.5 ms vs 935.9 ms respectively, p 0.005 ; . This corresponded to resting heart rates of 60.4 bpm for Europeans and 65.9 bpm for South Asians. This difference persisted after adjustment for age, beta-blocker use, fasting glucose and BP p 0.031 ; . No other ethnic differences in HRV BRS were detected. The most consistent correlate of HRV BRS measures was fasting glucose unadjusted mean RR interval beta -0.246, p 0.006 ; . The relationship coefficient ; -0.192, p 0.031, baroreflex between fasting glucose and HRV BRS was seen in both ethnicities. Similar correlations -0.189, existed with the HOMA index of insulin resistance mean RR interval p 0.036, baroreflex -0.209, p 0.022 ; . Surprisingly, there was no association between HbA1c and HRV BRS. CONCLUSIONS: South Asian men have higher resting heart rates than European men which may contribute to their greater CHD risk. This was still evident after adjusting for potential confounders and normal risk factors, implicating an unidentified risk factor linked to South Asian ethnicity.

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